ID 21-81

Registered: 2004.06.01   Last update: 2018.04.05
Gene Name potassium channel, subfamily K, member 5 Gene Symbol Kcnk5
Chromosome 14 Genomic Location chr14:20,959,000-21,002,000
Synonyms TASK-2, 3KCNK5b, Ayu21-84Imeg, Gt(Ayu21)84Imeg, Gt(pU21)84Imeg
Links UCSC Genome Browser(chr14:20,959,000-21,002,000)
NCBI Gene(16529)
IGTC(Kcnk5,5077)
UNIGene(Mm.68998)
MGI(1336175)
KEGG GENES(mmu:16529)
EST Profile(mm.68998)
Other Clone Trapped This Gene
Trap Vector pU-21 Cell Line KTPU10 Method 5'-RACE
Accession AB187250 GSS Location chr14:21,000,489-21,000,729 Size 240
Sequence CCGGAGTGNTGGAATTANGGGACTCTTTNTCCAGGAGGTGGCCATTCCAGAGTCATGGTGGACCG
GGGTCCTTTACTCACCTCGGCCATCATATTCTACCTGGCCATCGGGGCAGCGATCTTCGAAGTGC
TGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAACTACTATACACAGAAACTGCATCTACTCAAG
GAGTTTCCGTGCCTGAGTCAGGAGGGACTGGACAAGATCCTACAG
Links UCSC Browser(chr14:21,000,489-21,000,729)
IGTC(Ayu21-81)

Homology Search Results

[BC058164] Mus musculus potassium channel, subfamily K, member 5, mRNA (cDNA clone MGC:67981 IMAGE:5323480), complete cds.

Mouse Information

Card ID 439
Strain Name B6;CB-Kcnk5Gt(Ayu21)81Imeg
Internal Code Ayu21-81
Description This clone was isolated by using the exchangeable gene trap vector;pU-21, and feeder free ES cell line; KTPU10 (F1 of B6 and CBA). Mouse line has been established from this clone, and deposited to the CARD R-BASE.
[Paper] "TASK-2: a K2P K(+) channel with complex regulation and diverse physiological functions." Cid, L. P., Roa-Rojas, H. A., Niemeyer, M. I., Gonzalez, W., Araki, M., Araki, K., Sepulveda, F. V., Frontiers in Physiology, 4, 198 (2013). doi: 10.3389/fphys.2013.00198. PubMed ID:23908634.
[Paper]"Pathophysiological significance of the two-pore domain K(+) channel K2P5.1 in splenic CD4(+)CD25(-) T cell subset from a chemically-induced murine inflammatory bowel disease model." Nakakura, S., Matsui, M., Sato, A., Ishii, M., Endo, K., Muragishi, S., Murase, M., Kito, H., Niguma, H., Kurokawa, N., Fujii, M., Araki, M., Araki, K. and Ohya, S., Frontiers in Physiology, 6, 299 (2015). doi: 10.3389/fphys.2015.00299. PubMed ID:26578971.
Links IMSR (for Kcnk5)